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>   home   >   Products   >   Primary Antibodies   >   ICAM-2 Antibody   

ICAM-2 Antibody

Rabbit Polyclonal Antibody

     
  • WB - ICAM-2 Antibody ABV10714-30
    Western blot analysis of ICAM-2 in lysates from Jurkat cells (Lane 1& 2) and 3T3 cells (Lane 3).
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession P35330
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 31390 Da
Additional Information
Gene ID 15896
Positive Control Western Blot: Jurkat cell lysate and 3T3 cell lysate. IHC: spleen tissue
Application & Usage Western blotting (0.5-4 µg/ml) and Immunohistochemistry (5 µg/ml). It detects multiple isoforms of ICAM-2. However, the optimal concentrations should be determined individually.
Other Names ICAM1 , P3.58 , BB2 , CD54
Target/Specificity ICAM-2
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsICAM-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Icam2
Synonyms Icam-2
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Cellular Location Membrane; Single-pass type I membrane protein. Cell projection, microvillus. Note=Co-localizes with RDX, EZR and MSN in microvilli.
Tissue Location Expressed in endothelial cells and leukocytes. High levels found in lung
Citations (0)
citation

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Background

Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are tho µght to play an important role in embryogenesis and development. The family contains NCAM (for neuronal cell adhesion molecule), ICAM (for intercellular adhesion molecule), VCAM (vascular cell adhesion molecule), PECAM-1 (platelet/endothelial cell adhesion molecule-1), etc. ICAM-2 is involved in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion.

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Discontinued
Cat# ABV10714-30
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