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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   MC4 Receptor Antibody   

MC4 Receptor Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P56450
Other Accession NP_058673
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 36959 Da
Additional Information
Gene ID 17202
Positive Control 3T3 cell lysate
Application & Usage Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. 3T3 cell lysate can be used as a positive control.
Other Names melanocortin receptor 4, melanocortin 4 receptor, melanocortin-4 receptor
Target/Specificity MC4 Receptor
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-MC4 Receptor polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsMC4 Receptor Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Mc4r
Function Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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MC4R (Melanocortin-4 receptor) belongs to the GPCR superfamily that is responsible for multiple signal transduction pathway which includes the cAMP and MAPK signaling pathways. Expression of MC4R has been reported in brain. From genetic studies of mice and humans, it was established that MC4 receptor plays a critical role in appetite regulation. Mutation in the MC4R gene is associated with obesity in humans.

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$ 245.00
Cat# ABV10724
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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