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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ALK-7 Antibody   

ALK-7 Antibody

Rabbit Polyclonal Antibody

  • WB - ALK-7 Antibody ABV10726
    Western blot analysis of ALK 7 with lysate from rat kidney tissue (Lane 1) and Jurkat cells (Lane 2 & 3).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8K348
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 54700 Da
Additional Information
Gene ID 269275
Positive Control Jurkat cell lysate, Rat kidney tissue lysate
Application & Usage Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate and rat kidney tissue lysate can be used as positive controls.
Other Names Activin receptor type-1C, Activin receptor type IC, ACTR-IC, Activin receptor-like kinase 7, ALK-7
Target/Specificity ALK-7
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-Adipsin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsALK-7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Acvr1c {ECO:0000312|EMBL:AAH28780.1}
Function Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in interdigital regions in developing limb buds.
Research Areas
Citations (0)

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ALK7 or ACVR1C is a type I receptor for TGFB superfamily of signaling protein. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.

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$ 245.00
Cat# ABV10726
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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