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>   home   >   Products   >   Primary Antibodies   >   Beta3-AR Antibody   

Beta3-AR Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P26255
Other Accession NP_037240.1
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 43146 Da
Additional Information
Gene ID 25645
Positive Control Rat kidney tissue lysate
Application & Usage Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. Rat kidney tissue lysate can be used as a positive control.
Other Names Beta-3 AR, beta 3-AR, Beta-3 adrenoceptor, beta3-adrenergic receptor, beta-3 adrenoreceptor
Target/Specificity AR-Beta3
Antibody Form Liquid
Appearance Colorless liquid
Formulation 200 µg (0.5 mg/ml) affinity purified rabbit anti-Beta3-AR polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsBeta3-AR Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Adrb3
Synonyms Adrb3r
Function Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location White and brown adipose tissues, and digestive tract
Citations (0)

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The neurotransmitter/hormone adrenaline (epinephrine, adrenalin) plays a central role in the mammalian stress response, increasing heart rate, raising blood pressure, and increasing blood glucose levels. Adrenaline activates both alpha-adrenergic receptors and beta-adrenergic receptors. There are mainly three subtypes of beta adrenergic receptors known, beta1, beta2, and beta3. These receptors are expressed primarily in the heart, respiratory tissue, and adipose tissue. Beta3-receptors are abundant in brown adipocytes and play vital roles in lipolysis and thermoregulation. Beta adrenergic receptors are gaining much interest among researches in the studies of type-2 diabetes mellitus and obesity. It is also being considered as a therapeutic target for heart failure.

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$ 265.00
Cat# ABV10727
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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