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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Rictor Antibody   

Rictor Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6QI06
Other Accession NP_084444
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 191570 Da
Additional Information
Gene ID 78757
Positive Control Jurkat, HeLa, 3T3 cell lysates
Application & Usage The antibody can be used for Western blotting (1–4 µg/ml).
Other Names RICTOR; DKFZp686B11164; KIAA1999; MGC39830; mAVO3
Target/Specificity Rictor
Antibody Form Liquid
Appearance Colorless liquid
Formulation 200 µg (0.5 mg/ml) affinity purified rabbit anti-Rictor polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsRictor Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Rictor {ECO:0000250|UniProtKB:Q6R327}
Function Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient- insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. Plays an essential role in embryonic growth and development.
Research Areas
Citations (0)

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Rictor is a component of a protein complex [mTORC2] that integrates nutrient- and growth factor-derived signals to regulate cell growth. Rictor also plays an essential role in Akt phosphorylation and signaling.

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$ 245.00
$ 89.00
Cat# ABV10745
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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