|Calculated MW||22931 Da|
|Application & Usage||Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human CNTF can be used as a positive control.|
|Other Names||Ciliary neurotrophic factor|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-human CNTF polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||CNTF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.|
|Tissue Location||Nervous system.|
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CNTF (Ciliary Neurotrophic Factor) is a potent neural factor that was originally characterized as a survivability factor for chick ciliary neurons in vitro. CNTF has also been shown to promote survivability and differentiation of other neuronal cell types. CNTF is a 22.9 kDa protein containing 200 amino acid residues.
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