|Calculated MW||26525 Da|
|Positive Control||Recombinant human FGF-8|
|Application & Usage||Western Blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human FGF-8 can be used as a positive control.|
|Other Names||Fibroblast growth factor 8, FGF-8, Androgen-induced growth factor, AIGF, Heparin-binding growth factor 8, HBGF-8, FGF8, AIGF|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-human FGF-8 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||FGF-8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (PubMed:16384934, PubMed:16597617, PubMed:8663044). Plays a role in neurite outgrowth in hippocampal cells (PubMed:21576111).|
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Provided below are standard protocols that you may find useful for product applications.
Fibroblast Growth Factor-8 (FGF-8) is also known as Androgen-induced Growth Factor (AIGF), a heparin binding growth factor, which stimulates the proliferation and activation of cells that express the FGF receptors. Recombinant human FGF-8 is a 22.4 kDa protein containing 193 amino acid residues.
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