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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Fractalkine Antibody   

Fractalkine Antibody

Rabbit Polyclonal Antibody

  • WB - Fractalkine Antibody ABV10824
    Western blot analysis using recombinant human Fractalkine. Lane 1: 1 μg; Lane 2: 250 ng
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P78423
Other Accession BAD92274
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 42203 Da
Additional Information
Gene ID 6376
Application & Usage Western blot analysis (0.5-4 µg/ml). Per researcher’s feedback, it can also be used in immunoprecipitation (4-8 µg/ml), and Immunohistochemistry (10-20 µg/ml). However, the optimal conditions should be determined individually.

Other Names Fractalkine; C-X3-C motif chemokine 1; Neurotactin; CX3C membrane-anchored chemokine; Small-inducible cytokine D1
Target/Specificity Fractalkine
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-Fractalkine polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsFractalkine Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CX3CL1
Synonyms FKN, NTT, SCYD1
Function The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas
Research Areas
Citations (0)

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Fractalkine, also known as neurotactin, is a membrane-bound CX3C Chemokine. The mature protein is part of a 397-amino acid precursor and consists of a chemokine domain of 76 amino acids, a mucin stalk of 241 amino acids, a putative transmembrane domain of 18 amino acids, and an intracellular tail of 37 amino acids. Within the chemokine domain, the first two cysteine residues are separated by 3 amino acids (CX3C). Fractalkine message is found in high abundance in the brain, kidney, lung and heart tissues. Fractalkine is chemotactic for monocytes and other leukocytes including NK cells and may play a role in brain inflammation.

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$ 245.00
$ 89.00
Cat# ABV10824
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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