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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   IL-17A Antibody   

IL-17A Antibody

Rabbit Polyclonal Antibody

  • E - IL-17A Antibody ABV10833
    To detect hIL-17A by sandwich ELISA (using 100 μl/well antibody solution) a concentration of 0.5 - 2.0 μg/ml of this antibody is required. This antibody allows the detection of at least 0.2 - 0.4 ng/well of recombinant hIL-17A.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16552
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 17504 Da
Additional Information
Gene ID 3605
Positive Control ELISA: Recombinant hIL-17A
IHC: Human breast invasive ductal carcinoma tissue section
Application & Usage 1) WB: Use 0.1-0.2 µg/ml. The detection limit for recombinant human IL-17A is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
2) ELISA: Use 0.5 - 2.0 µg/ml (100 µl/well antibody solution)
3) Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of hIL-17A (50.0 ng/ml), a concentration of 0.9-1.3 µg/ml of this antibody is required.
4) Immunohistochemistry: 0.25 µg/ml with an overnight incubation at 4°C.
Other Names CTLA-8, IL-17, IL-17A, Cytotoxic T-lymphocyte associated antigen 8
Target/Specificity IL-17A
Antibody Form Liquid
Appearance Liquid
Formulation A sterile filtered antibody solution in PBS, pH 7.2.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsIL-17A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL17A
Synonyms CTLA8, IL17
Function Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.
Cellular Location Secreted.
Tissue Location Restricted to activated memory T-cells.
Research Areas
Citations (0)

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The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells.

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$ 245.00
Cat# ABV10833
(40 western blots)
Availability: 5-7days
Bulk Size
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