|Application ||WB, E|
|Calculated MW||21841 Da|
|Application & Usage||Western blot analysis (0.5-4 µg/ml). Recombinant human IGF-I. However, the optimal conditions should be determined individually.|
|Other Names||IGF1, IGF-1, IGF 1, Insulin like growth factor-1, Insulin like growth factor 1|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-human IGF-I polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||IGF-I Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation.|
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Provided below are standard protocols that you may find useful for product applications.
IGF-I (Insulin-like Growth Factor-I) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. Human IGF-I is a 7.6 kDa protein containing 70 amino acid residues.
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