|Application ||WB, E|
|Calculated MW||24384 Da|
|Application & Usage||Western Blotting (0.5-4.0 µg/ml). Per researcher’s feedback the antibody also works well in Neutralization (2-4 µg/ml). However, the optimal condition should be determined individually.|
|Other Names||IL-6, IL6, IL 6, Interluekin-6, Interluekin 6, interluekin|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-murine IL-6 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||IL-6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.|
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Provided below are standard protocols that you may find useful for product applications.
IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. Human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.
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