|Calculated MW||38235 Da|
|Application & Usage||Western blot analysis (0.5-1 µg/ml), Elisa (1-4 µg/ml) and neutralization (0.1-0.5 µg/ml). However, the optimal conditions should be determined individually.|
|Other Names||IL-12, IL12, IL 12, Interluekin-12, Interluekin 12. interluekin|
|Formulation||100 µg (0.5 mg/ml) antigen affinity purified goat anti-murine IL-12 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, and 0.02% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||IL-12 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.|
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Provided below are standard protocols that you may find useful for product applications.
IL-12 is a regulatory protein produced by activated B-lymphocytes and macrophages. Murine IL-12 is a 75 kDa heterodimeric glycoprotein (506 amino acids) consisting of disulfide linked 35 kDa (p35) and 40 kDa (p40) subunits.
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