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LIF Antibody

Rabbit Polyclonal Antibody

  • WB - LIF Antibody ABV10873
    Western blot analysis using recombinant human LIF. Lane 1; 100 ng; Lane 2: 200 ng; Lane 3: 500 ng
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P15018
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 22008 Da
Additional Information
Gene ID 3976
Application & Usage The antibody can be used for Western blot analysis (0.5-1 µg/ml), ELISA (2-3 µg/ml), and neutralization (0.5-1 µg/ml). However, the optimal conditions should be determined individually.
Target/Specificity LIF
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) antigen affinity purified rabbit anti-human LIF polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol and 0.02% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsLIF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LIF
Synonyms HILDA
Function LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
Cellular Location Secreted.
Research Areas
Citations (0)

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Leukemia Inhibitory Factor (LIF) is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. LIF has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, tho µgh mouse LIF is about 1000 fold less active on human cells, than human LIF.

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$ 245.00
$ 89.00
Cat# ABV10873
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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