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>   home   >   Products   >   Primary Antibodies   >   MIP-1-alpha Antibody   

MIP-1-alpha Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P50229
Reactivity Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 10335 Da
Additional Information
Gene ID 25542
Application & Usage Western blot analysis (0.5-4 µg/ml) and immunoprecipitation (4-8 µg/ml). However, the optimal conditions should be determined individually.
Other Names MIP-1, MIP1, MIP 1, MIP-1a, MIP 1a, MIP 1 alpha, macrophge inhibitory protein-1 alpha, macrophge inhibitory protein 1 alpha, macrophge inhibitory protein
Target/Specificity MIP-1a
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) immunoaffinity purified rabbit anti-rat MIP-1α polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsMIP-1-alpha Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ccl3
Synonyms Mip1a, Scya3
Function Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin.
Cellular Location Secreted.
Citations (0)

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MIP-1α (macrophage inflammatory protein-1α is a 60-amino acid CC chemokine with a molecular weight of 7.9 kDa. MIP-1α induces migration of monocytes/macrophages, B-lymphocytes, activated CD8+ T cells, natural killer (NK) cells, eosinophils. MIP-1α also stimulates basophils to release histamine, induces ICAM-1 expression, mast cell degranulation, and production of TNF-α, IL-1 and IL-6. In addition to its proinflammatory activities, MIP-1α inhibits the proliferation of hematopoietic stem cells in vitro and in vivo.

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$ 265.00
Cat# ABV10879
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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