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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CRIM1 Antibody (CT)   

CRIM1 Antibody (CT)

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NZV1
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG1
Calculated MW 113738 Da
Additional Information
Gene ID 51232
Positive Control Western Blot: Jurkat cell lysate
Application & Usage Western Blot: 1 - 2 µg/ml, ELISA. However, the optimal conditions should be determined individually.
Other Names Cysteine rich transmembrane BMP regulator 1 (chordin-like), CRIM-1, Cysteine-rich motor neuron 1 protein, Cysteine-rich repeat-containing protein S52
Target/Specificity CRIM1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (1 mg/ml) in 1X PBS containing 0.02 % sodium azide.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsCRIM1 Antibody (CT) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRIM1
Synonyms S52
Function May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface.
Cellular Location Processed cysteine-rich motor neuron 1 protein: Secreted
Tissue Location Expressed in pancreas, kidney, skeletal muscle, lung, placenta, brain, heart, spleen, liver and small intestine. Expressed in blood vessels (at protein level)
Research Areas
Citations (0)

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CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.

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$ 325.00
Cat# ABV10890
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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