|Calculated MW||29355 Da|
|Positive Control||Recombinant human NT-3|
|Application & Usage||The antibody can be used in Western Blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human NT-3 can be used as a positive control.|
|Other Names||NTF3; NT3; HDNF; MGC129711; NGF-2; NGF2|
|Formulation||200 µg (0.5 mg/ml) affinity purified rabbit anti-human NT-3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5mM EDTA and 0.01% thimerosal|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||NT-3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Seems to promote the survival of visceral and proprioceptive sensory neurons.|
|Tissue Location||Brain and peripheral tissues.|
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Provided below are standard protocols that you may find useful for product applications.
NT-3 is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. The active form of human NT-3 is a dimer, formed by two identical 119 amino acid subunits, which is held together by strong hydrophobic interactions.
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