|Calculated MW||13532 Da|
|Application & Usage||Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Recombinant human Apo-SAA can be used as a positive control. The antibody recognizes ~13 kDa recombinant human Apo-SAA. Reactivity to other species has not been tested.|
|Other Names||apo-lipoprotein, apolipoprotein, apolipoprotein-SAA, apolipoproteinSAA, apolipoprotein SAA, apo-SAA, apoSAA, apo SAA|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 0.5% BSA, 30% glycerol and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||ApoSAA Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Major acute phase protein.|
|Tissue Location||Expressed by the liver; secreted in plasma (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Human apo-SAA is a 104 amino acid polypeptide that circulates primarily in association with high-density lipoproteins (HDL). The level of apo-SAA, normally 1-5 µg/ml in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL apo-lipoprotein. The human SAA gene codes for a 122 amino acid polypeptide, which contains an 18 amino acid N-terminal signal sequence.
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