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TNF-beta Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P01374 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 22297 Da |
| Gene ID | 4049 |
|---|---|
| Application & Usage | Western blot analysis (0.5-1 µg/ml) and Neutralization (2-5 µg/ml). However, the optimal conditions should be determined individually. |
| Other Names | TNF-b, TNF b, TNFbeta, tnf, tumor necrosis factor, tumor necorsis factor beta, TNF superfamily member 2, Lymphotoxin-alpha; LT-alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1; Flags: Precursor. |
| Target/Specificity | TNF-b |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5 mg/ml) purified rabbit anti-human TNF-β polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol and 0.02% sodium azide. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | TNF-beta Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LTA |
|---|---|
| Synonyms | TNFB, TNFSF1 |
| Function | Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (PubMed:9462508). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo. |
| Cellular Location | Secreted. Membrane. Note=The homotrimer is secreted. The heterotrimer is membrane-associated |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Tumor Necrosis Factor-beta (TNF-β) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. Human TNF-β is an 18.6 kDa protein containing 171 amino acid residues.
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