|Application ||WB, IHC|
|Calculated MW||26625 Da|
|Positive Control||Recombinant human 4-1BBL|
|Application & Usage||Western Blot analysis (0.5-4.0 µg/ml) and Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually.|
|Other Names||TNFSF9, CD137L, 41BBL, 4 1BBL|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti-human 4-1BBL polyclonal antibody in PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||4-1BBL Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed in brain, placenta, lung, skeletal muscle and kidney|
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Provided below are standard protocols that you may find useful for product applications.
Human 4-1BB Ligand (4-1BBL) is a member of the emerging family of Ligands with structural homology to tumor necrosis factor. Human 4-1BBL is a 19.5 kDa protein containing 185 amino acid residues, comprising the TNF-like extra-cellular domain of 4-1BBL.
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