4-1BBL Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
---|---|
Primary Accession | P41273 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 26625 Da |
Gene ID | 8744 |
---|---|
Positive Control | Recombinant human 4-1BBL |
Application & Usage | Western Blot analysis (0.5-4.0 µg/ml) and Immunohistochemistry (5 µg/ml). However, the optimal conditions should be determined individually. |
Other Names | TNFSF9, CD137L, 41BBL, 4 1BBL |
Target/Specificity | 4-1BBL |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-human 4-1BBL polyclonal antibody in PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
Handling | The antibody solution should be gently mixed before use. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | 4-1BBL Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TNFSF9 |
---|---|
Function | Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation- induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. |
Cellular Location | Membrane; Single-pass type II membrane protein. |
Tissue Location | Expressed in brain, placenta, lung, skeletal muscle and kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
Human 4-1BB Ligand (4-1BBL) is a member of the emerging family of Ligands with structural homology to tumor necrosis factor. Human 4-1BBL is a 19.5 kDa protein containing 185 amino acid residues, comprising the TNF-like extra-cellular domain of 4-1BBL.
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