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STOX1 Antibody (CT)

Rabbit Polyclonal Antibody

  • WB - STOX1 Antibody (CT) ABV10950-100
    Western blot analysis of STOX1 in human liver tissue lysate with STOX1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6ZVD7
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG1
Calculated MW 110962 Da
Additional Information
Gene ID 219736
Positive Control Western Blot: Human liver tissue lysate
Application & Usage Western Blot: 1 µg/ml, ELISA. However, the optimal conditions should be determined individually.
Other Names Storkhead-box protein 1, C10orf24, winged-helix domain-containing protein, PEE4
Target/Specificity STOX1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (1 mg/ml) in 1X PBS containing 0.02 % sodium azide.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsSTOX1 Antibody (CT) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STOX1
Synonyms C10orf24
Function Involved in regulating the levels of reactive oxidative species and reactive nitrogen species and in mitochondrial homeostasis in the placenta (PubMed:24738702). Required for regulation of inner ear epithelial cell proliferation via the AKT signaling pathway (By similarity).
Cellular Location Isoform A: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=In epithelial cells, diffusely expressed in the cytoplasm, particularly in peri-membrane cortical regions (By similarity). Concentrated at centrosomes during metaphase (PubMed:22253775). {ECO:0000250|UniProtKB:B2RQL2, ECO:0000269|PubMed:22253775} Isoform C: Nucleus, nucleolus.
Tissue Location Expressed in placenta, including the invasive extravillus trophoblast cells.
Citations (0)

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STOX1 (Storkhead box 1), also known as PEE4 or C10orf24, is a winged-helix domain containing transcription factor believed to play a role in the differentiation of stem cells. As a DNA-binding protein, STOX1 exists as three alternatively spliced isoforms, designated A, B and C, all of which localize to either the cytoplasm or the nucleus. Defects in STOX1 are the cause of pre-eclampsia/eclampsia 4 (PEE4), also known as gestational proteinuric hypertension. STOX1 was also found to be functionally involved in late-onset Alzheimer's disease.

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$ 325.00
Cat# ABV10950-100
Availability: 5-7days
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