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Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P35411 |
| Other Accession | NP_598218.1 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 40327 Da |
| Gene ID | 171056 |
|---|---|
| Application & Usage | Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Blocking peptide is available separately |
| Other Names | CX3CR1, C-X-C chemokine receptor type 3, C-X-C chemokine receptor type-3, CXCR-3, CXCR3, CXCR 3, Interferon-inducible protein 10 receptor, RBS111 |
| Target/Specificity | CX3CR1/RBS11 |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | CX3CR1/RBS11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Cx3cr1 |
|---|---|
| Synonyms | Rbs11 |
| Function | Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:P49238}; Multi-pass membrane protein |
| Tissue Location | Most abundant in adult spinal cord, brain, kidney, gut, uterus and testes. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Human CX3CR1 has been shown to mediate both the adhesive and migratory functions of fractalkine. Fractalkine and CX3CR1 represent new types of leukocyte trafficking regulators.
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