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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   PAI-1 Antibody   

PAI-1 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P20961
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 45010 Da
Additional Information
Gene ID 24617
Application & Usage Western blot analysis (1-2 µg/ml). However, the optimal conditions should be determined individually. The antibody detects rat PAI-1. Cross reactivity of the antibody to other species has not been determined.
Other Names PAI1, PAI 1, PAI, PAI-1, Plasminogen activator inhibitor , Endothelial plasminogen activator inhibitor
Target/Specificity PAI-1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) protein A affinity purified rabbit anti-PAI-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 0.1% BSA, 0.02% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsPAI-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Serpine1
Synonyms Pai1, Planh1
Function Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis (By similarity).
Cellular Location Secreted.
Research Areas
Citations (0)

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PAI-1 (plasminogen activator inhibitor-1) is originally cloned from human endothelial cell and rat hepatoma cell cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI-1 inhibits both tissue-type palsminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA). High PAI-1 levels are associated with an increased risk of thromboembolic disease while PAI-1 deficiency may represent an inherited autosomal recessive bleeding disorder.

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$ 265.00
Cat# ABV11009
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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