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Galectin-7 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P47929 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 15075 Da |
| Gene ID | 3963;653499 |
|---|---|
| Application & Usage | Western blot analysis (0.5-4 µg/ml). Per researcher’s feedback, it can also be used in neutralization (5-10 µg/ml). However, the optimal conditions should be determined individually. Recombinant human Galectin-7 can be used as a positive control. |
| Other Names | Galectin7, Galectin 7, Galectin-7, Gal-7; Gal7, GAL7, GAL-7, HKL-14; PI7; p53-induced gene 1 protein, lectin |
| Target/Specificity | Galectin-7 |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-human Galectin-7 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | Galectin-7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LGALS7 |
|---|---|
| Synonyms | PIG1 |
| Function | Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. |
| Cellular Location | Cytoplasm. Nucleus. Secreted. Note=May be secreted by a non-classical secretory pathway |
| Tissue Location | Mainly expressed in stratified squamous epithelium. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Galectin-7 belongs to growing family of evolutionary conserved animal lectins. Galectins consists of beta-galactoside binding lectins that contain homologous carbohydrate recognition domains (CRDs). Galectin has the ability to induce apoptosis of activated T-cells and T-leukaemia cell lines. Other activities include cell differentiation and inhibition activity of CD45 protein phosphatase activity. Galectin also binds beta-galactoside as well as CD45, CD3 and CD4. Recombinant Human Galectin-7 is a 15.4 kDa protein consisting of 136 amino acid residues.
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