|Reactivity||Human, Mouse, Rat|
|Application & Usage||Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually.|
|Other Names||Increased in High Glucose Protein 2, IHG-2, Down-regulated in Mos-transformed cells protein, Drm, Cysteine knot superfamily 1, BMP antagonist 2, Protein related to DAN and cerberus, DAN domain family member 3|
|Formulation||100 µg (0.5 mg/ml) affinity purified polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||Gremlin-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Gremlin (also known as Increased in High Glucose Protein 2, IHG-2, Down-regulated in Mos-transformed cells protein, Drm) functions as a bone morphogenetic protein (BMP) antagonist. It acts by binding to, and forming heterodimers with BMP-2, BMP-4, BMP-7, thus preventing them from interacting with their cell surface receptors.
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