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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Galectin-3 Antibody   

Galectin-3 Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P17931
Other Accession NP_002297
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 26152 Da
Additional Information
Gene ID 3958
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate can be used as a positive control. The antibody recognizes the 30 kDa human Galectin-3 in Western blot analysis with Jurkat cell lysate.
Other Names Galectin3, Galectin 3, Galectin-3, Galactoside binding protein, GALBP, GAL3 , GAL 3, GAL-3, Galactose-specific lectin 3, Laminin-binding protein, MAC 2 antigen, MAC2, Lectin L-29, L-34 galactoside-binding lectin
Target/Specificity Galectin 3
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-human Galectin-3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsGalectin-3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MAC2
Function Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Cellular Location Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface
Tissue Location A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages Expressed in fetal membranes.
Research Areas
Citations (0)

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Galectins are a family of soluble β-galactoside-binding animal lectins that modulate cell-to-cell and cell-to-ECM interactions, as well as apoptosis. Galectin-3 encodes a 30-35 kDa protein containing a single carbohydrate binding domain, which binds galactose-containing glycoconj µgates. Upregulated expression of Galectin-3 is involved in cancer progression and metastasis.

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$ 245.00
$ 89.00
Cat# ABV11045
(40 western blots)
Availability: 5-7days
Bulk Size
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