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IL-12p40 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P29460 |
| Other Accession | NP_002178 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 37169 Da |
| Gene ID | 3593 |
|---|---|
| Application & Usage | Western blot analysis (0.5-4 µg/ml). It detects mainly the 40 kDa of IL-12p40 isoform, and in a lesser extent the 35 kDa of IL-12p35 isoform. Recombinant human IL-12 can be used as a positive control. However, the optimal conditions should be determined individually. |
| Target/Specificity | IL-12 |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-human IL-12 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | IL-12p40 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IL12B |
|---|---|
| Synonyms | NKSF2 |
| Function | Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Interleukin-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Recombinant Human IL-12 p40 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 306 amino acids fragment (23-328).
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