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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Endostatin Antibody   

Endostatin Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P39059
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 141720 Da
Additional Information
Gene ID 1306
Positive Control Recombinant human endostatin
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually.
Other Names Endostatin-XV, Related to endostatin:Restin
Target/Specificity Endostatin
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-human Endostatin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5mM EDTA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsEndostatin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name COL15A1
Function Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Expressed predominantly in internal organs such as adrenal gland, pancreas and kidney
Research Areas
Citations (0)

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Endostatin has been identified as a C-terminal fragment of Collagen type 18, a recently identified member of a family of collagen-like proteins referred to as multiplexin family Endostatin specifically inhibits proliferation of endothelial cells altho µgh it does not affect the proliferation of EOMA cells. Endostatin also potently inhibits angiogenesis and tumor growth. Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization. Endostatin can be found in vessel walls (elastic fibers) and basement membranes. Recombinant Endosatin expressed in yeast causes G1 arrest of endothelial cells, and endostatin treatment results in apoptosis of HUVE and HMVE cells.

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$ 245.00
$ 89.00
Cat# ABV11070
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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