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>   home   >   Products   >   Primary Antibodies   >   DNA Methyltransferase 2 (Clone 102B1259.2) Antibody   

DNA Methyltransferase 2 (Clone 102B1259.2) Antibody

Mouse Monoclonal Antibody

  • WB - DNA Methyltransferase 2 (Clone 102B1259.2) Antibody ABV11109
    Lane1: DNMT2 transfected cell lysate(15μg/ml)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O55055
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype Mouse IgG1κ
Clone Names 102B1259.2
Calculated MW 46794 Da
Additional Information
Gene ID 13434
Positive Control Western blot: DNMT2 transfected cell lysate
Application & Usage Western blot: 1-3 µg/ml. However, the optimal conditions should be determined individually.
Other Names DNMT2
Target/Specificity DNMT2
Antibody Form Liquid
Appearance Colorless liquid
Formulation 50 µg of antibody in 100 µl PBS containing 0.2% gelatin and 0.05% sodium azide.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsDNA Methyltransferase 2 (Clone 102B1259.2) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Trdmt1
Synonyms Dnmt2, Met2
Function Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).
Cellular Location Nucleus.
Tissue Location Highly expressed in thymus, testis, and at much lower levels in spleen, lung, brain, heart, kidney, liver, skeletal muscle and embryonic stem cells
Citations (0)

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Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. DNMT2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation. DNMT2 contains all the sequence motifs diagnostic of DNA (cytosine-5)-methyltransferases but appears to lack the large N-terminal regulatory domain common to other eukaryotic methyltransferases.

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$ 225.00
Cat# ABV11109
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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