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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   Irisin Antibody   

Irisin Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NAU1
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 23659 Da
Additional Information
Gene ID 252995
Application & Usage Western Blot - 1: 1000 dilution
Other Names Fibronectin Type III Domain-containing Protein 5 (cleaved); Fibronectin Type III Repeat-containing Protein 2 (cleaved); FNDC5 (cleaved)
Target/Specificity Irisin
Antibody Form Liquid
Appearance Colorless liquid
Formulation 1 mg/ml in PBS containing 10% glycerol and 0.02% sodium azide.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsIrisin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FNDC5
Synonyms FRCP2
Function Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.
Cellular Location Cell membrane; Single-pass type I membrane protein Peroxisome membrane; Single-pass type I membrane protein. Note=Imported in peroxisomes through the PEX5 receptor pathway.
Tissue Location Widely expressed, with highest levels in heart. Very low expression, if any, in colon, pancreas and spleen
Research Areas
Citations (0)

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Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.

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$ 325.00
Cat# ABV11191
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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