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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   IL-10 Antibody   

IL-10 Antibody

Rabbit Polyclonal Antibody

  • WB - IL-10 Antibody ABV11194
    Western blot with IL-10 antibody. Lane 1: Jurkat cell lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P22301
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 20517 Da
Additional Information
Gene ID 3586
Positive Control Western Blot: Jurkat cell lysate
Application & Usage Western blot: 1:200
Other Names CSIF, IL-10, IL10A, TGIF, B-TCGF, GVHDS, MGC126450, MGC126451, RP11-262N9.1, Interleukin-10
Target/Specificity IL-10
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg or 30 µg (0.5 mg/ml) of antibody in PBS containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH7.2
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsIL-10 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL10
Function Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
Cellular Location Secreted.
Tissue Location Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types
Research Areas
Citations (0)

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IL-10 (Interleukin-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF), is an 20.5 kDa protein containing 161-178 amino acid residues. IL10 is produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.

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$ 275.00
$ 89.00
Cat# ABV11194
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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