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SPHKAP Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q2M3C7 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 186456 Da |
| Gene ID | 80309 |
|---|---|
| Positive Control | Western blot: Jurkat Cell lysate |
| Application & Usage | Western blot: 1-4 µg/ml. |
| Other Names | A-kinase anchor protein SPHKAP, SPHK1 interactor, AKAP domain containing, DKFZp781H143, DKFZp781J171, KIAA1678, MGC132614 antibody, MGC132616, SKIP antibody, A-kinase anchor protein Sphingosine kinase type 1-interacting protein, SPHK1 (Sphingosine kinase type 1) interacting protein, SPHK1-interactor and AKAP domain-containing protein, SPHK1 interactor, AKAP domain. |
| Target/Specificity | SPHKAP |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg or 30 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | SPHKAP Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SPHKAP |
|---|---|
| Synonyms | KIAA1678, SKIP |
| Function | Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1. |
| Cellular Location | Cytoplasm. Note=Colocalizes with SPHK1 in the cytoplasm |
| Tissue Location | Highly expressed in heart. Both isoforms abundantly expressed in ventricle. Also expressed in spleen, ovary and brain |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1.
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