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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >   PSGL-1 Antibody   

PSGL-1 Antibody

Rabbit Polyclonal Antibody

  • WB - PSGL-1 Antibody ABV11209
    Western blot of PSGL-1/CD162 antibody with Jurkat cell lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14242
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 43201 Da
Additional Information
Gene ID 6404
Positive Control Western blot: Jurkat Cell lysate
Application & Usage Western blot: 1-4 µg/ml.
Other Names PSGL, CD162, SELPLG, CLA, CD162, PSGL1, Selectin P ligand.
Target/Specificity PSGL-1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg or 30 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsPSGL-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed on neutrophils, monocytes and most lymphocytes
Research Areas
Citations (0)

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PSGL-1 (P-Selectin glycoprotein ligand, also designated CD162), exists as a disulfide-linked homodimer. PSGL-1 is a type 1 membrane protein that localizes on the tips of microvilli of leukocytes. Its extracellular domain is rich in serines, threonines and prolines, and includes a series of 15 and 16 decameric repeats in HL-60 and U-937 cells, and human leukocytes, respectively. Although PSGL-1 appears to be the sole receptor for P-Selectin on human hematopoietic cells, it also interacts with E-Selectin through a unique binding site. In order to bind PSGL-1 to either E-Selectin or P-Selectin, PSGL-1 must be sialylated and fucosylated. PSLG-1 is a mucin-like molecule, much like leukosialin (CD43), CD164 and CD34. These proteins belong to an emerging family of cell adhesion receptors called sialomucins, which transduce negative signals in hematopoietic cells.

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$ 275.00
$ 89.00
Cat# ABV11209
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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