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IL-1RA Antibody

Rabbit Polyclonal Antibody

  • WB - IL-1RA Antibody ABV11217
    Western blot of IL-1RA antibody. Lane 1: Recombinant human IL-1RA protein - 2 ng. Lane 2: Recombinant human IL-1RA protein - 10 ng
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P18510
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 20055 Da
Additional Information
Gene ID 3557
Positive Control Western Blot: Recombinant protein
Application & Usage Western blot: 1-4 µg/ml.
Other Names IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430, human IL-1RA, recombinant human IL-1RA
Target/Specificity IL-1RA
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsIL-1RA Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL1RN
Synonyms IL1F3, IL1RA
Function Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
Cellular Location Isoform 1: Secreted. Isoform 3: Cytoplasm.
Tissue Location The intracellular form of IL1RN is predominantly expressed in epithelial cells
Research Areas
Citations (0)

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Interleukin-1 RA is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1-alpha (IL1A) and interleukin 1-beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. IL1RA Human Recombinant produced in E.Coli is a non-glycosylated, N-terminal methionyl form of the human naturally-occurring polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton.

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$ 265.00
$ 89.00
Cat# ABV11217
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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