|Calculated MW||40418 Da|
|Positive Control||Western Blot: Recombinant protein|
|Application & Usage||Western blot: 1-4 µg/ml.|
|Other Names||INT1L1, IRP, Int-1-like protein 1, Int-1-related protein|
|Formulation||100 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||Wnt-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Expressed in brain in the thalamus, in fetal and adult lung and in placenta.|
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Provided below are standard protocols that you may find useful for product applications.
This protein belongs to the Wnt family of proteins. The WNT gene family consists of structurally related genes that encode secreted signaling proteins involved in the Wnt signaling pathway. Wnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt-2 is expressed in brain in the thalamus, in fetal and adult lung and in the placenta.
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