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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   TDRD4 Antibody   

TDRD4 Antibody

Rabbit Polyclonal Antibody

  • WB - TDRD4 Antibody ABV11225
    Western blot of TDRD4 antibody. Lane 1: Recombinant rh- TDRD410 ng. Lane 2: Recombinant rh- TDRD4 50 ng
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BXT8
Other Accession  Q9BXT8
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 184643 Da
Additional Information
Gene ID 56163
Positive Control Western Blot: Recombinant protein
Application & Usage Western blot: 1-4 µg/ml.
Other Names RING finger protein 17, Tudor domain-containing protein 4, TDRD4, RNF17
Target/Specificity TDRD4
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsTDRD4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RNF17
Synonyms TDRD4
Function Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad- MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity).
Cellular Location Cytoplasm. Nucleus. Note=Predominantly found in the cytoplasm Component of a nuage in male germ cells (an electron-dense spherical cytoplasmic body present in late pachytene and diplotene spermatocytes and in elonging spermatids) (By similarity)
Tissue Location Testis specific.
Research Areas
Citations (0)

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Tudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The Tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The Tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc. TDRD4 is a candidate CT antigen expressed in a subset of liver cancers

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$ 265.00
$ 89.00
Cat# ABV11225
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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