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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SAHH/AHCY Antibody   

SAHH/AHCY Antibody

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23526
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 47716 Da
Additional Information
Gene ID 191
Positive Control Western Blot: Jurkat cell lysate, mouse muscle lysate, rat kidney lysate, recombinant protein
Application & Usage Western blot: 1-4 µg
Other Names SAHH, AdoHcyase, S-adenosyl-L-homocysteine hydrolase, Adenosyl Homocysteinase
Target/Specificity SAHH/AHCY
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsSAHH/AHCY Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SAHH
Function Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.
Cellular Location Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Research Areas
Citations (0)

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AHCY (EC is an enzyme that catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). AHCY controls the intracellular S-adenosylhomocysteine (SAH) concentration that is crucial for transmethylation reactions. AHCY deficiency causes hypermethioninemia.

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$ 245.00
$ 89.00
Cat# ABV11235
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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