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CRP Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P02741 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 25039 Da |
| Gene ID | 1401 |
|---|---|
| Positive Control | Western Blot: Jurkat cell lysate, mouse muscle lysate, rat kidney lysate, recombinant protein |
| Application & Usage | Western blot: 1-4 µg |
| Other Names | C-Reactive Protein |
| Target/Specificity | CRP |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin®, and 50 % glycerol. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | CRP Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CRP |
|---|---|
| Synonyms | PTX1 |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| Cellular Location | Secreted. |
| Tissue Location | Found in plasma. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
C-Reactive protein (CRP) is an acute-phase protein that can have both pro-and anti-inflammatory effects. CRP is synthesized by the liver in response to factors released by fat cells or adipocytes. CRP is a member of the pentaxin family of proteins and in its native form is composed of five identical subunits, non-covalently linked to form a symmetrical disc of ~ 115 KDa. Widely used as a clinical marker of the state of inflammation. Increased CRP levels are found in inflammatory conditions including: bacterial infection, rheumatic fever, active arthritis, myocardial infarction, malignancies and in the post-operative state.
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