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ApoA4 Antibody (NT)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P06727 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 45372 Da |
| Gene ID | 337 |
|---|---|
| Positive Control | Western blot: Jurkat, K562, NCI-H460 cell lysate, IHC: human hepatocarcinoma tissue. |
| Application & Usage | Western blot: ~1:1000, IHC: ~1:10-1:50. |
| Other Names | APOA4; Apolipoprotein A-IV; Apolipoprotein A4 |
| Target/Specificity | ApoA4 |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µl of antibody in PBS with 0.09% (W/V) sodium azide |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | ApoA4 Antibody (NT) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | APOA4 |
|---|---|
| Function | May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. |
| Cellular Location | Secreted. |
| Tissue Location | Synthesized primarily in the intestine and secreted in plasma |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Apolipoproteins are plasma lipoproteins that function as transporters of lipids and cholesterol in the circulatory system. Chylomicrons are a fundamental class of apolipoproteins containing very low-density lipoproteins (VLDL), intermediate-density lipoproteins (IDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL). Apolipoprotein A-IV (ApoA4) is a glycoprotein that exists as a free apolipoprotein in human plasma. ApoA4 activates the lecithin cholesterol acyl transferase to modulate the rate of lipid transfer protein (LTP) activity. Additional evidence suggests that ApoA4 may also act as an antioxidant to inhibit LDL oxidation in the atherosclerosis model.
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