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ApoA5 Antibody (NT)

Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6Q788
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 41213 Da
Additional Information
Gene ID 116519
Positive Control Western blot: HL60 cell lysate, IHC: human hepatocarcinoma tissue
Application & Usage Western blot: ~1:1000, IHC: ~1:10-1:50.
Other Names APOA5; RAP3; Apolipoprotein A-V; Apolipoprotein A5; Regeneration-associated protein 3
Target/Specificity ApoA5
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µl of antibody in PBS with 0.09% (W/V) sodium azide
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsApoA5 Antibody (NT) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name APOA5
Synonyms RAP3
Function Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages.
Cellular Location Secreted.
Tissue Location Liver and plasma.
Research Areas
Citations (0)

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Apolipoproteins are plasma lipoproteins that function as transporters of lipids and cholesterol in the circulatory system. The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5.

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$ 245.00
Cat# ABV11267
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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