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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Aldolase C (ALDOC) Antibody (CT)   

Aldolase C (ALDOC) Antibody (CT)

Rabbit Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession P09972
Reactivity Human, Mouse, Rat, Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 39456 Da
Additional Information
Gene ID 230
Positive Control Western blot: human brain tissue lysate, IHC: human brain cerebellum.
Application & Usage Western blot: ~1:1000, IHC: ~1:10-1:50.
Other Names ALDOC; ALDC; Fructose-bisphosphate aldolase C; Fructose-bisphosphate aldolase C; Brain-type aldolase
Target/Specificity ALDOC
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µl of antibody in PBS with 0.09% (W/V) sodium azide
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsAldolase C (ALDOC) Antibody (CT) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ALDOC
Synonyms ALDC
Research Areas
Citations (0)
citation

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Background

Fructose 1, 6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1, 6-bisphosphate. Fructose 1, 6-bisphosphate aldolase exists as three forms, the muscle-specific Aldolase A, the liver-specific aldolase B, and the brain-specific aldolase C. Aldolase A, B, and C arose from a common ancestral gene, from which aldolase B first diverged. Aldolase A is one of the most highly conserved enzymes known, with only about 2% of the residues changing per 100 million years. Aldolase B is regulated by the hormones insulin and glucagon and has been implicated in hereditary fructose intolerance disease. Aldolase C is a polypeptide that is exclusively expressed in Purkinje cells. Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase C-negative Purkinje cells.

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Discontinued
Cat# ABV11306-100
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