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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ANGPTL1 Antibody (NT)   

ANGPTL1 Antibody (NT)

Rabbit Polyclonal Antibody

  • FC - ANGPTL1 Antibody (NT) ABV11311-100
    ANGPTL1 Antibody flow cytometric analysis of Hela cells(right histogram)compared to a negative control cell(left histogram). Fitch-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95841
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 56720 Da
Additional Information
Gene ID 9068
Positive Control Western blot: HeLa cell lysate, IHC: Human placenta tissue, FACS: HeLa cells.
Application & Usage Western blot: ~1:1000, IHC: ~1:50-1:100, FACS: ~1:10–1:50.
Other Names ANGPTL1; ANG3; ANGPT3; ARP1; Angiopoietin-related protein 1; Angiopoietin-3; Angiopoietin-like protein 1
Target/Specificity ANGPTL1
Antibody Form Liquid
Appearance Colorless liquid
Formulation 100 µl of antibody in PBS with 0.09% (W/V) sodium azide
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsANGPTL1 Antibody (NT) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ANG3, ANGPT3, ARP1
Cellular Location Secreted.
Tissue Location Highly expressed in adrenal gland, placenta, thyroid gland, heart, skeletal muscle and small intestine. Weakly expressed in testis, ovary, colon, pancreas, kidney and stomach
Research Areas
Citations (0)

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Angptl1 (angiopoietin-like 1), also known as angioarrestin, ARP1, ANGPT3 or previously known as angiopoietin 3 (ANG3), is a member of the angiopoietin-like family. It is highly expressed in adult tissues, particularly adrenal gland, thyroid, placenta and small intestine. Angptl1 exists as a disulfide-linked dimer and shares 45.1% identity with Ang-1 and 59% identity with Angptl2. Angptl1 consists of an N-terminus with a coiled-coil domain, potential glycosylation sites and a C-terminus with a fibrinogen-like domain. It is a secreted protein but does not function as a growth factor in endothelial cells. Angptl1 plays a distinct role in the regulation of angiogenesis; inhibiting proliferation, migration, tube formation and endothelial cell adhesion. To exert this inhibitory activity, Angptl1 is speculated to interact with a receptor on endothelial cells. In a wide variety of tumor tissues, Angptl1 expression is down-regulated suggesting that a major function of this protein involves its antiangiogenic properties.

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$ 245.00
Cat# ABV11311-100
Availability: 5-7days
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