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>   home   >   Products   >   Primary Antibodies   >   C-Kit/CD117 Antibody (NT)   

C-Kit/CD117 Antibody (NT)

Rabbit Polyclonal Antibody

  • FC - C-Kit/CD117 Antibody (NT) ABV11320
    Flow cytometric analysis of Hela cells using KIT Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • WB - C-Kit/CD117 Antibody (NT) ABV11320
    The anti-KIT Pab is used in Western blot to detect KIT in serum-starved HeLa cell lysate (lane 1) and primate testis tissue lysate (lane 2).
  • IHC - C-Kit/CD117 Antibody (NT) ABV11320
    Purified rabbit anti-KIT Pab was used in immunohistochemistry on Breast Carcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Additional Information
Positive Control Western blot: HeLa cell lysate, IHC: Breast carcinoma, FACS: Hela cells.
Application & Usage WB: 1:1000, IHC: 1:10 – 1:50, IF: 1:10 – 1:50.
Other Names KIT, Mast/stem cell growth factor receptor, Proto-oncogene tyrosine-protein kinase Kit
Target/Specificity c-Kit/CD117
Antibody Form Liquid
Appearance Colorless liquid
Formulation 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsC-Kit/CD117 Antibody (NT) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Citations (0)

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The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell proliferation, apoptosis, and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto-oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.

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$ 245.00
Cat# ABV11320
(40 western blots)
Availability: 5-7days
Bulk Size
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