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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   VCAM-1/CD106 Antibody (Center)   

VCAM-1/CD106 Antibody (Center)

Rabbit Polyclonal Antibody

  • WB - VCAM-1/CD106 Antibody (Center) ABV11325
    CD106 Antibody western blot analysis in mouse NIH-3T3 cell line lysates (35 μg/lane).
  • WB - VCAM-1/CD106 Antibody (Center) ABV11325
    CD106 Antibody western blot analysis in HepG2 cell line lysates (35 μg/lane).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P19320
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 81276 Da
Additional Information
Gene ID 7412
Positive Control Western blot: NIH-3T3 and HepG2 cell lysates.
Application & Usage WB: 1:1000.
Other Names VCAM1; L1CAM; Vascular cell adhesion protein 1; INCAM-100
Target/Specificity VCAM1
Antibody Form Liquid
Appearance Colorless liquid
Formulation In PBS with 0.09% (W/V) sodium azide.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsVCAM-1/CD106 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name VCAM1
Synonyms L1CAM
Function Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue
Research Areas
Citations (0)

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Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors including neuroblastoma, rhabdomyosarcoma, Wilms’ tumors, Ewing’s sarcomas and some primitive myeloid malignancies. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the B2å1 and B2åM integrins. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM) -like protein and is deleted in 66% of patients with Kallmann's syndrome, anosmia with secondary hypogonadism.

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$ 245.00
Cat# ABV11325
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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