|Application ||WB, IHC|
|Reactivity||Human, Mouse, Rat, Pig, Bovine|
|Calculated MW||34074 Da|
|Positive Control||WB: Jurkat cells, mouse liver, rat liver, whole cell lysates, IHC: human lung cancer|
|Application & Usage||WB: 1:500 - 1:1000, IHC: 1:100 – 1:200|
|Other Names||CCNG; CYCG1; Cyclin-G1; Cyclin-G|
|Formulation||1 mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||Cyclin G1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).|
|Cellular Location||Nucleus. Note=DNA replication foci after DNA damage|
|Tissue Location||High levels in skeletal muscle, ovary, kidney and colon|
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Provided below are standard protocols that you may find useful for product applications.
Cyclin-G1 (CCNG1) belongs to the cyclin family and contains the cyclin box. CCNG1 may have a part in growth regulation and is associated with G2/M phase arrest in response to DNA damage. CCNG1 may be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation. The CCNG1 protein lacks the protein destabilizing (PEST) sequence which is present in other family members.
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