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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   CD54 (ICAM1) FITC Monoclonal Antibody (Clone 15.2)   

CD54 (ICAM1) FITC Monoclonal Antibody (Clone 15.2)

Mouse Monoclonal Antibody

  • FC - CD54 (ICAM1) FITC Monoclonal Antibody (Clone 15.2) ABV11481
    Human peripheral blood lymphocytes were stained with FITC 15.2 with relevant isotype control in Red.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05362
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse IgG1
Clone Names 15.2
Calculated MW 57825 Da
Additional Information
Gene ID 3383
Positive Control FACS: Human peripheral blood lymphocytes
Application & Usage Flow (Cell Surface): 5 µl/1x10^6 cells, Volume per test: 5 µl (0.5 µg).
Other Names CD54/ICAM1
Target/Specificity CD54/ICAM1
Antibody Form Liquid
Appearance Colorless liquid
Formulation Phosphate-buffered aqueous solution pH 7.2, ≤0.09% Sodium azide, may contain carrier protein/stabilizer.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage 4°C
Background Descriptions
PrecautionsCD54 (ICAM1) FITC Monoclonal Antibody (Clone 15.2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ICAM1
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Inter-Cellular Adhesion Molecule 1 (ICAM-1), also known as Cluster of Differentiation 54 (CD54), is a member of the immunoglobulin superfamily, and is a cell surface glycoprotein which is typically expressed in low concentrations on endothelial cells and cells of the immune system. The protein encoded by this gene is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells. Upon cytokine stimulation, the concentrations greatly increase. ICAM-1 can be induced by interleukin-1 (IL-1) and tumor necrosis factor alpha (TNFα) and is expressed by the vascular endothelium, macrophages, and lymphocytes. ICAM-1 is a ligand for LFA-1 (integrin), a receptor found on leukocytes. When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 and then transmigrate into tissues. ICAM-1 has been implicated in subarachnoid hemorrhage (SAH). Levels of ICAM-1 are shown to be significantly elevated in patients with SAH over control subjects in many studies. ICAM-1 expressed by respiratory epithelial cells is also the binding site for rhinovirus, the causative agent of most common colds. The 15.2 antibody reacts with the 85-110 kDa ICAM-1.

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$ 135.00
$ 295.00
Cat# ABV11481
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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