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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   P-glycoprotein Antibody   

P-glycoprotein Antibody

Rabbit Polyclonal Antibody

  • IHC - P-glycoprotein Antibody ABV11487
    IHC(F):Mouse Intestine
  • IHC - P-glycoprotein Antibody ABV11487
    IHC(F):Rat Kidney
  • IHC - P-glycoprotein Antibody ABV11487
    IHC(P):Mouse Kidney
  • IHC - P-glycoprotein Antibody ABV11487
    IHC(P):Rat Kidney
  • IHC - P-glycoprotein Antibody ABV11487
    IHC(P):Human lung cancer
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P08183
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 141479 Da
Additional Information
Gene ID 5243
Positive Control IHC: Mouse Kidney, Mouse Intestine, Rat Kidney, Human Lung Cancer tissue
Application & Usage IHC: 1:500-1:1000 of 0.5 mg/ml stock
Other Names P-gp, Multidrug resistance protein 1, MDR1, ATP-binding cassette sub-family B (MDR/TAP) member 1, ABCB1
Target/Specificity P-glycoprotein
Antibody Form Lyophilized
Appearance Solid
Formulation Each vial contains 5mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3
Handling The vial should be centrifuged to collect the lyophilized solid before reconstituting
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsP-glycoprotein Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ABCB1
Synonyms MDR1, PGY1
Function Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Cellular Location Cell membrane; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}
Tissue Location Expressed in liver, kidney, small intestine and brain
Research Areas
Citations (0)

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P-gp, also called MDR1 or ABCB1, is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of xenobiotics across extra- and intracellular membranes). It is an ATP-dependent drug efflux pump with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein functions in the kidneys, liver, blood–brain barrier and the intestinal epithelium.

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$ 325.00
Cat# ABV11487
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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