|Reactivity||Human, Mouse, Rat|
|Formulation||100 µg (0.5 mg/ml) affinity purified rabbit anti- TCTN1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Precautions||TCTN1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
TCTN1 belongs to the Tectonic protein family that regulate Hedgehog (Hh) pathway. During neural tube development, TCTN1 is required for the formation of most ventral cell types and for full Hh pathway activation. At later stages in development, TCTN1 is tho µght to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
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