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>   home   >   Products   >   Primary Antibodies   >   PARP (Cleaved) Antibody   

PARP (Cleaved) Antibody

Purified Rabbit Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11103.3
Other Accession NP_031441
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Additional Information
Other Names PARP1, ADPRT, PPOL, NAD(+) ADP-ribosyltransferase 1
Target/Specificity PARP (Cleaved)
Format 100 µg (0.5 mg/ml) affinity purified rabbit anti-cleaved PARP polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsPARP (Cleaved) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Citations (0)

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PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, is a highly conserved nuclear enzyme implicated in DNA repair and in the apoptosis response of cells. This protein can be cleaved by many caspases in vitro and is one of the main cleavage targets of caspase-3 in vivo. The cleavege occurs between ASP214 and Gly 215, which separates PARP’s N-terminal DNA binding domain (24 kDa) from its C-terminal catalytic domain (89 kDa). It has been shown that cleavage of PARP facilitates cellular disassembly and inhibition of PARP cleavage attenuates apoptosis in vitro.

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$ 365.00
Cat# ABV11502
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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