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SIAH3 Antibody

Purified Rabbit Polyclonal Antibody

  • WB - SIAH3 Antibody ABV11518
    Western blot analysis of SIAH3 with rat kidney tissue lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IW03
Other Accession NP_001178047.1
Reactivity Human, Mouse, Rat, Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 30660 Da
Additional Information
Gene ID 283514
Other Names Seven in absentia homolog 3, Siah-3, SIAH3
Target/Specificity SIAH3
Format 100 µg (0.5 mg/ml) affinity purified rabbit anti-SALL1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsSIAH3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SIAH3
Function Negative regulator of PARK2 translocation to damaged mitochondria. Acts probably by destabilizing PINK1 protein, hence inhibiting PARK2 targeting to dysfunctional depolarized mitochondria.
Cellular Location Mitochondrion.
Citations (0)

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SIAH-3 is a member of the seven in absentia homolog protein family. SIAH3 contains one SIAH-type zinc finger and is encoded by a gene located on human chromosome 13. SIAH families are components that mediate ubiquitination and subsequent proteasomal degradation of target proteins.

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$ 245.00
Cat# ABV11518
(40 western blots)
Availability: 5-7days
Bulk Size
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