|Other Names||FLJ10052 antibody, MGC126430 antibody, MGC126431 antibody, SLEB1 antibody, TIL 3 antibody, TIL3 antibody, TLR 5 antibody, Tlr5 antibody, TLR5 antibody, Toll like receptor 5 antibody, Toll like receptor 5 precursor antibody, Toll-like receptor 5 antibody, Toll/interleukin 1 receptor like protein 3 antibody, Toll/interleukin-1 receptor-like protein 3 antibody.|
|Format||100 ml protein A purified rabbit anti-TLR5 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 10% glycerol and 0.02% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Precautions||TLR5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology(TH) domain,which is essential for Toll-induced signal transduction.TLR1,as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride(LPS) stimulation, which results in the activation and translocation of NFkB and suggests that these receptors are involved in mediating inflammatory responses. TLR6 is highly homologous to TLR1, and like other members of TLR family, it induces NFkB Signaling upon activation. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes.
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